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Moreover, the AP, which is situated in the caudal brainstem and is part of the dorsal vagal complex (DVC), which also includes the nucleus of the solitary tract (NTS) and the dorsal motor nucleus of the vagus (DMV), acts as a critical nucleus where peripheral ghrelin transmits orexigenic messages

At we see the use of well-tolerated biomimentic therapies like during drug holiday phases or as a long-term strategy for those who cannot continue with GLP-1s

First-time prescribing of AOMs also decreased in September 2025, relative to June 2025 (-9.5%)

Mullins RJ, Mustapic M, Chia CW, et al

PubMed , JAMA , vol

An absolute risk of 2.3%